Rational design of mRNA nanovaccine for cancer immunotherapy
Messenger RNA (mRNA) vaccines are revolutionizing the therapy of cancer. They can be flexibly developed in a short period of time, allowing transient expression of multiple antigens for safe and efficient immunization. A diversity of mRNA vaccines is being explored in clinic to benefit patients with cancer.
However, the translation of mRNA vaccines is still hampered by multistage delivery barriers before initiating strong immunity,…
The paper (on which this article is based) is published in the journal National Science Review.